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>My father has recently been requested to participate in a study of a new drug >called Tasmar, aka- Tolcapone. Has anyone else been approached to participate >in this study or know anything about this drug? My dad has not responded to >any other medications- including Sinemet- maybe that is why they chose him, >but the letter indicates differently. I am just looking for anyone else that >is considering participating in the study. Please email me at >[log in to unmask] or respond on the listserv for eveyones' benifit. Thank you >for your time. Hi Gail: I have been involved with the Canadian study of Tolcapone for more than two months. I'm on the last stage, and for me it has been great . It is designed for people who have "end of dose drop off", and it has allowed me to reduce my pill-taking times to three a day from four. This has made a big difference in my life. I can now enjoy almost an entire day of "ons". However, it is not for everyone; there have been a few minor problems. If you need more data, let me know. All the Best, Brian Black