On Fri, 21 Feb 1997 18:42:30 -0500 "Brian C.Black" <[log in to unmask]> writes: >>My father has recently been requested to participate in a study of a >new drug >>called Tasmar, aka- Tolcapone. Has anyone else been approached to >participate >>in this study or know anything about this drug? My dad has not >responded to >>any other medications- including Sinemet- maybe that is why they >chose him, >>but the letter indicates differently. I am just looking for anyone >else that >>is considering participating in the study. Please email me at >>[log in to unmask] or respond on the listserv for eveyones' benifit. >Thank you >>for your time. >Hi Gail: >I have been involved with the Canadian study of Tolcapone for more >than two >months. I'm on the last stage, and for me it has been great . It is >designed for people who have "end of dose drop off", and it has >allowed me >to reduce my pill-taking times to three a day from four. This has >made a >big difference in my life. I can now enjoy almost an entire day of >"ons". >However, it is not for everyone; there have been a few minor problems. > If >you need more data, let me know. >All the Best, Brian Black > Brian, I have "end-of-dose-drop-off." I'm sure many of us do. Is there someone on our list who can help me to know more about Tolcapone? Especially, I want to understand how it is supposed to work at the chemical and cellular level. I need medications every 3 hours around the clock (8 x per day). Thanks a million, Ivan Suzman, Portland, Maine 47/10 40 deg. F> raining and almost springlike