Here is something I've been wondering about. My doctor tells me that the substantia nigra (SN) produces dopamine which is a neurotransmitter for controlling many important bodily functions. Does a healthy SN produce dopa at a constant rate all the time like a faucet turned on at one flow level? Or does it sometimes turn off, slow down or increase the flow? Does the SN simply try to keep a fixed concentration of dopa in the brain? If it isn't a constant flow, what determines the amount of dopa to be generated at any given time? Anyone have an explanation that I could understand? Ron Reiner