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I hesitate to post the following information because I don't want to get folks all excited over what MAY be just a fluke or a coincidence. However, I don't see how I can NOT post it either. So please keep in mind that this is very possibly just an anomaly... I went to the MD last Friday, Feb. 21, with what turned out to be an infection. I was prescribed FLAGELLA 500mg to be taken 2 times daily for one week. Within 36 hours of beginning the drug, I began to feel physically "light..." as in "airy." This was an entire-body-experience. By the following day, after I'd taken the Flagyl for two full days and one 1/2 day (totaling 5 tablets at that point), I felt strange and after thinking about it for a bit, realized that the "strange feeling" was the fact that I felt NORMAL... i.e. much as I did before the PD struck. I've now been taking Flagyl for six days. While I continued to take my usual Sinemet twice daily about every 5 to 6 hours the first day on the Flagyl, by the second day I felt no physical NEED for it (tho logically I KNEW I had to continue taking it). Since the second day, I've taken the Sinemet 8 hours apart. I've taken it every 8 hours or so, and that was because I was hesitant to just up and stop taking it entirely. There are so few PD symptoms left as of this moment that I felt compelled to post here. I'm calling my MD tomorrow and asking if Flagyl can be taken on a daily basis in order to test the drug. If it can be, I plan on staying at the 500mg dose for one more week and then reducing the amount I'd take by half. IF I remain essentially symptomsless at that dosage I'll drop down to 1/4 of a tablet twice a day. If anyone else has had a similar experience while taking Flagella, I'd really like to hear from ya. And I'll keep this group updated about this phenomena. I have no answers if you have any in-depth questions about the above. I have no idea WHY Flagella appears to work. And I sure hate to get all excited about this when it's to all intents and purposes could be nothing. Barb Mallut [log in to unmask]