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Ivan, Except for Lisa's remark about being a "born-again virgin," I noticed no female responses on this subject. I think perhaps no increase in libido has been noted for females because no studies have been done on the subject. As usual, males have been the subject of medical research. Perhaps I can engender a few responses. In talking with fellow female PWP's (is that an oxymoron?), my experience is not universal. Nevertheless, I definitely respond in a sexual way to sinemet. When it is working optimally, I feel quite sexy; when I'm "off," I could care less, which is just as well, since performance is impossible. All I am capable of then is what my husband calls the "dead elk syndrome:" just lie there and do nothing. Naturally, fatigue plays a role, as it does with everyone. If sexual encounters are timed so they take place when energy and interest are at their peak, it can be a rewarding experience. I rarely experienced multiple orgasms before l-dopa; now they're routine. When I was on eldepryl, however, I was a sex maniac. Luckily, I had to stop taking it for other reasons; I was getting into real trouble there. Don't bother contacting me if your sex life needs a boost; I'm monogamously married, though my husband is having trouble keeping up with me. Hope this posting isn't too x-rated for the post, but I'd be interested in other female PWP's experiences - all in the name of research, of course. pine`