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Barb: Your note regarding the antibiotics sparked a memory I had completely forgotten about. Since I was diagnosed with PD six years ago, I've been forced to take antibee's several times. (Sorry, don't rememeber the names.) Usually for a sinus infection. I swallowed those things three or four times a day for at least two weeks. Once, because of a relapse, I took an antibee for a month. As soon as I started any antibee, the working life of my Sinemet almost doubled. The one time I was forced to take the drug for a month, I don't beleive I ever had an "off" period the entire time while taking small doses of Sinemet three times a day. (Of course, this was only two-and-one-half years after diagnosis, so I was still fairly normal.) After this happened three times, I mentioned it to my neuro. Figured I would at least be awarded the Novel Prize or something similar for this amazing discovery. He laughed, jotted down a note, and said he would check with his research friends to see if any studies had ever been done. As far as I know, he never followed through. The last time I took any antibee's was about four months ago. (Again, a sinus infection.) Effect on the Sinemet was not quite so dramatic, but the effective life of the pills still was extended. Who knows? Maybe we've stumbled onto something. Or maybe the AMA and the drug companies --- along with the United Nations, the Zionist Occupational Government, the World Bank, the liberal media, the movie industry and Jane Fonda --- are involved in a conspiracy to keep this from all us Parkies. Seriously, I'm interested in the further developments with your meds. Keep us posted. As Barb asked in her original message, anyone else had similar experiences with antibiotics? Any theories, Brian? Get well . . . and keep laughing. Stan Houston (54/6) Cat Spring, Texas 78933 [log in to unmask]