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As anyone with PD knows, stress is closely related to PD symptoms. According to our morbid anatomy friends by the time a PWP is diagnosed, they have lost 80 percent or more, of their striatal substantia nigra. Now, let's suppose that a pre-PWP has lost, say, 50 percent, then that person is subjected to stress (bereavement- job-marriage etc). I think it is a reasonable supposition that the stress reacts with the latent PD to produce the first signs of what is to come. These may well disappear with time, but the underlying disease continues it's progress and is ultimately recognized for what it is. In other words, stress doesn't cause PD, it simply aggravates the symptoms and sometimes this can be the first sign that something is amiss. Take Care, M. CG for Margaret (65/27 yrs) ~~~~~~~~~~~~~~~~~~~~~~ At 17:00 9/03/97 -0500, Sonia Neilson wrote: >Hello Boyd. >Thank`s for your answer. Like you the one of my friends (Marie 45) feel >sure, that she also had got P:S because of stress. >The other one (Ann 56) ARE sure that she got the desease some years after >devorsing. >I `m convinsed that the symptoms started 1 year after my dear husb. passed >away from a hartattack 10 years ago, he was only 51 and I 48 years old. My >right leg was hanging , and it was difficult for me to walk, and today it`s >much worser. I got the diagnose about 3 years ago, but with Sinemet and >Permax, I have many "golden" days. >I had discussed it with two of our experts - Professor Parkenberg and Dr. >Dupont - and both told me, that they can deneigh our theori. Of course we >are born with the genes, but I`m glad that other Parkinson patient have the >samefeeling like us. ~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~ Mark Atyeo 51 Alexander Mackie Circuit Isaacs, 2607 Australia +61 6 286 2606 Time flies like an arrow, fruit flies like an apple.