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Hello Brian, Brian Collins wrote: > > On Sun 09 Mar, Joao Paulo Carvalho wrote: > > Charles Countryman wrote: > > >es, > > > > Against facts there is no arguments...There are old hands in this list > > that take Sinemet for a long time and found it was the better choice > > since then as for ex. Brian and others.If I were you I would check with > > at the least 3 other specialists and then judge. > > > > Hello Joao Paulo, I must have missed your initial email , but I have seen the > replies. I am, as you indicate, an advocate of early introduction of Sinemet/ > Madopar, with one proviso: that the sinemet is used only to replace the > missing natural dopamine, and not taken in large doses as I now understand > some people use it. Using that philosophy (At least in more recent years as > I learned more about it), I have managed to make effective use of Sinemet > for 17 years. <snipped> > I can see that, by advocating the early introduction of Sinemet, I may have > appeared to be arguing against the use of agonists, although I am sure that > I have not specifically said so. To set the record straight, I consider that > for the long-term Sinemet user, the introduction of a modest dose of levodopa > agonist can be beneficial in promoting smoother transitions between on and > off. Sorry if I have misled anyone. > Dear friend, I may assure you that at least in my case you did not misled about only take levodopa.Neverthless at my present probation with PD I only take levodopa and 400 u of vitamin E and has worked fine to me so far. Best wishes, +----| Joao Paulo de Carvalho |------ + | [log in to unmask] | +--------| Salvador-Bahia-Brazil |------+