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Dear All, My mother (89) currently takes [155 mg carbidopa + 1550 mg Levodopa] (as Sinemet) daily, and has also just begun taking NADH (with her skeptical neuro's reluctant approval). The dose I'm giving her is 1 NADH tablet (1.8 mg per tablet) with each of her 7 daily Sinemet-doses. I've read here in the PD Digest that some people are effectively using 5mg per dose or 15 mg per day (?) of NADH -- so this means that Mom is now getting 7 x 1.8mg = 12.6mg NADH daily at present. Is there any means of judging whether this amount should be increased/decreased? I certainly want to see this help her -- she has been having mild tremors most of the time, prior to starting NADH yesterday evening -- but I also don't want to overdose her on NADH or cause unwanted side-effects. -- SJS