Lisa wrote: >does any one know any more about the complete loss of desire (sexual) >and sinemet, are there any legit studies? any info? Help my marrage is >in jeopardy... >[log in to unmask] Hello Lisa: Here are a few "legit studies" on sexual function and PD. These abstracts and millions of others can be found by searching MEDLINE. This is a free source, one of the websites MEDLINE can be accessed is http://www.healthgate.com Title Sexual problems in young patients with Parkinson's disease. Author Wermuth L; Stenager E Address Department of Neurology, Odense University Hospital, Denmark. Source Acta Neurol Scand, 1995 Jun, 91:6, 453-5 Abstract The purpose of this study was to describe sexual function in a representative group of young patients with Parkinson's disease PD). Twenty-five patients (15 men, 10 women; age range 36-56 yrs) participated in a structured interview on sexual function. Forty percent of the men and 70% of the women reported changed libido while 33.4% of the men and 80% of the women experienced changed sexual activity after onset of PD. A tendency to changes in libido and sexual function was seen with increasing time of treatment and advanced Hoehn-Yahr stages. It is concluded that changes in libido and sexual function occur more frequently than previously reported, especially in women, and more attention should be paid to these problems. Language of Publication LA=ENG Unique Identifier 96012346 =================== Title Treatment of fluoxetine-induced sexual dysfunction with bupropion: a case report. Author Labbate LA; Pollack MH Address Walter Reed Army Medical Center, Department of Psychiatry, Washington, D.C. 20307. Source Ann Clin Psychiatry, 1994 Mar, 6:1, 13-5 Abstract Antidepressant-induced sexual dysfunction is a common and significant cause of patient distress and noncompliance with treatment. A number of adjunctive pharmacologic strategies, including yohimbine, cyproheptadine, bethanechol, and amantadine, have been employed previously. We report a case of using bupropion to treat fluoxetine-induced sexual dysfunction in a 50-year-old man with a history of recurrent major depression. This is the first case of such treatment we know. Sexual dysfunction induced by fluoxetine is thought secondary to effects on the serotonin system. Bupropion is an antidepressant with minimal sexual side effects. The mechanism by which bupropion resolved this sexual dysfunction is unknown, but it may be related to its mild dopamine uptake blockade. Language of Publication LA=ENG Unique Identifier 95039219 ================= Title Utility of the sickness impact profile in Parkinson's disease. Author Longstreth WT Jr; Nelson L; Linde M; MuAnoz D Address Division of Neurology, Harborview Medical Center, Seattle, WA 98104-2499. Source J Geriatr Psychiatry Neurol, 1992 Jul-Sep, 5:3, 142-8 Abstract The Sickness Impact Profile (SIP) is a questionnaire consisting of 136 items grouped into 12 categories and two dimensions (physical and psychosocial). To characterize its utility in Parkinson's disease (PD), we administered the SIP to 44 consecutive clinic patients with PD. Compared to 44 age- and sex-matched control subjects, PD patients had their greatest dysfunction in the categories of mobility, communication, and home management. The two items that PD patients most commonly endorsed were, "I am having trouble writing or typing" (75%) and, "My sexual activity is decreased" (61%). In general, these treated PD patients had greater dysfunction in the psychosocial than physical dimensions. Two simple PD-specific scales correlated well with the physical dimension score but less so with the psychosocial dimension, suggesting that the SIP assesses more functional domains than the PD-specific scales used. The SIP holds some promise as a broad measure of functional status in PD patients. Language of Publication LA=ENG Unique Identifier 92360126 >References: <Pine.SOL.3.91.970228063622.27997B-100000@winc0> > <[log in to unmask]> >Date: Fri, 7 Mar 1997 05:40:00 -0500 >Reply-To: "Parkinson's Information Exchange" <[log in to unmask]> >Sender: "Parkinson's Information Exchange" <[log in to unmask]> >From: LISA CRUMRINE <[log in to unmask]> >Organization: MOSAIC MADNESS >Subject: Re: Antw: Female sexuality and sinemet >To: Multiple recipients of list PARKINSN <[log in to unmask]> > >Ida Kamphuis wrote: >> >> Pine, you wrote >> >> > inemet. When it is working optimally, I feel quite sexy; when I'm >> > "off," I could care less, which is just as well, since performance is >> > impossible. All I am capable of then is what my husband calls the "dead >> > elk syndrome:" just lie there and do nothing. >> > >> > Naturally, fatigue plays a role, as it does with everyone. If sexual >> > encounters are timed so they take place when energy and interest are at >> > their peak, it can be a rewarding experience. >> >> Dear Pine >> >> I have the same experience you have. Sinemet working as a aphrodisiacum, but >> only with good timing. I am not an exception. In personal contacts the same has >> been told about 10 times. But it is neither a rule. The loss of all sexual >> sexual feeling is no exception too. And even in betrween; no change is >> possible. >> >> Ida Kamphuis >> Holland >does any one know any more about the complete loss of desire (sexual) >and sinemet, are there any legit studies? any info? Help my marrage is >in jeopardy... >[log in to unmask] > > Margaret Tuchman (55yrs, Dx 1980)- NJ-08540 [log in to unmask]