Good day, I rarely get questions from Becky to ask of the members of the PD list, but today I have one. She's starting seeing a new neurologist who doesn't seem to be quite so limited by (my perception) the "How you doing, here's your medication, PAY MY BILL, and I'll see you in a month" paradigm. This new neurologist has a newsletter named the "Townsend Letter for Doctors and Patients" from January 1997. Searching for the Townsend Letter on the Internet, I've found that it's focus is on alternative medicines. Within the January issue, is an article by Dr. David Perlmutter. I've also found his article on the web. Some excerpts as printed in the Townsend Letter follow: Parkinson's disease has, until now, been described as being exclusively a "brain disorder." Indeed, in 1960, researchers first demonstrated that a specific part of the brain called the basal ganglia functioned abnormally in Parkinson's disease. Various medicines were created to supply the brain chemicals missing in Parkinson's patients, and these medications remain the mainstay of treatment. Unfortunately, this approach is entirely symptomatic. This is to say that these medicines, although quite helpful in reducing the symptoms of Parkinson's disease, do nothing for the underlying disease process itself which typically worsens with time. New and exciting research has recently demonstrated that a majority of patients with Parkinson's disease have a defect in one or more liver enzymes which, when functioning normally, act to detoxify various environmental poisons to which we are exposed. Various epidemiological studies have demonstrated a significant increased incidence of Parkinson's disease in populations having a higher exposure to environmental toxins. In a fascinating report appearing in the Archives of Environmental Health (1990), Goldsmith found an extremely high incidence of Parkinson's disease on three adjacent kibbutzim in the Negev region of Israel whose water was supplied from wells draining a common aquifer. The incidence of Parkinson's disease was reported to be 500% greater in each of the three kibbutzim than in the remainder of the region. A history of occupational herbicide use has been described as significantly increasing risk of Parkinson's disease by about three fold with data also suggesting a dose response relationship between the duration of cumulative life time exposure to agricultural work and risk of Parkinson's disease. At a recent international symposium on Parkinson's disease, research was presented demonstrating a very high correlation between Parkinson's disease and the use of pesticides. In comparing one farming area southwest of Montreal where pesticides were used in large amounts to areas in the same region with low pesticide use, the incidence of Parkinson's disease was seven times greater in the former. Why wouldn't everyone with these types of toxic exposure develop Parkinson's disease? The answer may lie in the defective liver detoxifying enzymes described earlier. Thus, most people by virtue of having an adequate liver detoxification system, may not suffer significant ill effects when exposed to various environmental toxic insults. Parkinson's patients on the other hand, because of their defective liver enzyme systems, may actually potentiate relatively low-level neuro toxic chemicals allowing the brain to be damaged and producing Parkinson's disease. Recently, therapeutic techniques have been developed utilizing nutritional approaches in an attempt to enhance the function of the liver detoxification enzymes. In 1992, Dr. Jeffrey Bland described a nutritional intervention program designed to improve the function of these detoxification enzymes. His research demonstrated a significant increase in the liver's ability to detoxify various toxic substances after three weeks on a specific dietary program augmented in certain nutrients known to be helpful for liver function. ** end of quote from The Perlmutter Letter ** By visiting the following URL you can see the entire text of The Perlmutter Letter. http://www.perlhealth.com/smr_news.htm If any of you have trouble viewing this page and would like to see the balance of the article, please email me offline and I'll send you the balance of the article. (I may already be too long and haven't gotten to Becky's question yet. :-}) ) Within the text of the Townsend Letter is a reference to a product called UltraClear Plus along with other aspects of a protocol to detoxify the liver. Finally, the question. Have any of you heard of the Townsend Letter for Doctors and Patients or of the UltraClear Plus product? Have any of you tried UltraClear Plus? Have any of you followed a protocol for detoxifying the liver and if so, are you willing to share results? Thank you, Jeff Jones part time CG for Becky, Seattle, WA [log in to unmask] * The fellow who boasts of an open mind may only have a vacant one. *