---------- From: Byron, Sara Sent: Tuesday, March 04, 1997 9:48 AM To: owner-parkinsn Subject: RE: Migraines and question on Amantadine Our experience with amantadine and sinemet were mixed. Amantadine played a role in controlling dad's shaking and tremors. he used it for many years. As the PD progressed, however, the associated PD dementia increased to an intolerable level. We faced a permanent nursing home decision if the dementia could not be controlled. Our new neurologist proposed discontinuing the amantadine, as it can build up in the system adding to the dementia. We started weaning in early AUG 96., and the process didn't end until Nov. This was a terrible period for us as there were SERIOUS withdrawal problems - freezing (and I mean life a 150 pound rock - Mom and I swore that his feet grew roots into the ground) falling, hallucinations, anxiety attacks, perceived breathing problems, blood pressure swings. The lesson, I guess, is that this drug has its place, but should be monitored closely and carefully. BTW - Dad is shakier now, but the dementia is under control and he is still at home (with home health assistance, of course). We still take things one step at a time! Sara Byron daughter of Richard 79/28 yrs w PD ( and counting!) Hinsdale & Naperville, Illinois The following binary file has been uuencoded to ensure successful transmission. Use UUDECODE to extract. begin 600 WINMAIL.DAT M>)\^(A46`0:0"``$```````!``$``0>0!@`(````Y`0```````#H``$(@`<` M&````$E032Y-:6-R;W-O9G0@36%I;"Y.;W1E`#$(`0V`!``"`````@`"``$$ M@`$`%0```$%M86YT861I;F4O4WEM;65T<F5L`.,'`06``P`.````S0<#``X` M$``3``H`!0`7`0$@@`,`#@```,T'`P`.`!``$0`?``4`*@$!"8`!`"$````Q M,[log in to unmask],#$Q.#(Q130T-#4U,S4T,#`P,`"B!@$$D`8`+`$```$` M```,`````P``,`(````+``\.``````(!_P\!````30``````````8)1D8$&X M`0@`*RN**0``'T-=`&0`&@`O`!X````4`"=P87)K:6YS;B<`<&%R:VEN<VY` M;&ES='-E<G8N=71O<F]N=&\N8V$`````'@`",`$````%````4TU44``````> M``,P`0```!X```!P87)K:6YS;D!L:7-T<V5R=BYU=&]R;VYT;RYC80````,` M%0P!`````P#^#P8````>``$P`0````L````G<&%R:VEN<VXG```"`0LP`0`` M`",```!33510.E!!4DM)3E-.0$Q)4U1315)6+E543U)/3E1/+D-!```#```Y M``````L`0#H``````@[log in to unmask]@!,!@``$@````L` M(P```````P`F```````+`"D```````,`+@```````P`V``````!``#D``$JR MO<4PO`$>`'```0```"D```!213H@36EG<F%I;F5S(&%N9"!Q=65S=&EO;B!O M;B!!;6%N=&%D:6YE``````(!<0`!````&P````&\*+.,Z7MI]XN4;A'0@AY$ M15-4```"!'UN`0`#``80OQZ<8@,`!Q`C!```'@`($`$```!E````+2TM+2TM M+2TM+4923TTZ0EE23TXL4T%205-%3E0Z5%5%4T1!62Q-05)#2#`T+#$Y.3<Y M.C0X04U43SI/5TY%4BU005)+24Y33E-50DI%0U0Z4D4Z34E'4D%)3D5304Y$ M455%4P`````"`0D0`0```.,$``#?!```T@<``$Q:1G5HTF[/_P`*`0\"%0*D M`^0%ZP*#`%`3`U0"`&-H"L!S973N,@8`!L,"@S(#Q@<3`H.Z,Q,-?0J`",\) MV3L5_W@R-34"@`J!#;$+8&[P9S$P,Q0@"PH2\@P!&F,`0"`*A0J+;&DQY#0T M`M%I+1Q##-`<0]D+63$V"J`#8'0%D`5`OBT>YPJ''9L,,!YF1@-ACCH?[AYF M#((@0GD#8.1N+`8!<F$?CR"=!F`7`C`ASR+;5`I0<V1A&GDC\$T*P!&P(#`T M`2/P,3DY-R`Y.C0T.!-P321?()U4;Z,FGR+;;W=N!)`M"K$R:PN`<VXJ;R5N M=6).:AZA+(\BVU)%,;!-'FD)P`MQ!Y$`<&0@<;[log in to unmask]@00.!_0&0 M9#0A&N\+*!0B&G0>5\)/"'`@97AP!G$)\*AC92`#\'0I0&$UA]\T8P"0+H`' [log in to unmask]<!(;6EX"8`N(#5I(*T+47D)@#1@(`-@;#G`?0N`(`6@`C`]L1P@ M&0`@Z2BP9"<$(',1P"[Q/M"O-'(^8#M0!;!S/$%H.<#N=1'P-)`Y\"`"$`7` M`X'\>2`]4!'1/$($(#H`.<#\4$0]$`-@"<$$$`F`(_!R:"Y@978$D"/P0J)A M^000;V,',!Z0-)!"X0VP?P>``C`',#WQ!0!"`$#R=/YO-&$]\4:P/=`D,`)@ M.<"K/=!$$&P\05<YP&8`T,\]8SE1`X$F82!N"'`[(?\^T$/0!X!%<43@`)`U M$0:0IT*318<%H'5L-)!N'H#\(&(YP#XV/",X\BZ`!^!W+H`(<!6!9P0`!4`> M87"^;T#R-=`$\`(A"X!U/K)?1&,UAR/P1*!!(F,#D6(S4`!,,75P/?)"HG-Y M][log in to unmask]&0UT5`Q1L!+.O\\04A"-.`*P$42.Z``<#ZRBSX!0@%L0=!!54<I MX/PV+E$Q/^)`L1YA.;`$$?$UT&1N)P5`"?!2,47!D0,@3F]V/$%4:`0`[SG0 M45$]D!Z0<@401Y(Y4G\$<$%30.!10D*A.\$[HU-@15))3U4%\#GB9%\D,%H0 M`R`>84>1;00@+:M!4`G1>CZR*#1R23O@GU7!1\`&D#K!*9`U,#T0UPA@-(%7 MX6M><4T#<#1C_U^``^`%L#G`.@!%`$"@6>'_8!`[<0G!!^`#8!Z`46%'(?=" MDPG`8+(I/%!(@#Z30[&U93%U1.!N10`U`7-7,OIX")!T0=!%``&082!F@=LY M43FP:400-)!B1D$Z`/\^LEWV(_`"8&.P-)`>8$-A_PAP4M$#\!D`0'`V'%G` M1[+W1+$CX5^`9RB!9H%9X6)S\VBA6#%R=4H!45,$(`M1^SFP:8%U!4`_4$P3 M3*$$8/\#`$:P%@$^(!60$?!6D31R.U&P%@!F3"!6D#Q!0E3Z5UYQ1#7`;2(_ M4P203%'^=V\D2SM9X6#!<V$^-31COT"Q<N)9(77A8J%*,B@YX_]*(T"P!T`Z M`@003J$`<&\"[F]+$$P!$>$I2"1VI`&0WFMB4FJR-3%5$F528&*1^UI1!W$A M-APD$B.4-H4HL,UN(&A:<7E24FD1LC20\#<Y+S(J(".P6?%"THXH<31@L4_1 M9R$I-H6N2"\!*+`]T28'L&$Y4=9V=L%1(4D^DF\$`#8?^1OS,S8=9S?%'F8V MCQH("X:]%2$`BA```P`0$``````#`!$0`````$``!S#`N9J"Q3"\`4``"##` AN9J"Q3"\`1X`/0`!`````0`````````#``TT_3<``"H` ` end