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Dear Daphne-- I find it almost impossible to comprehend the horrors you have been through. Never heard of HYTRIN before, but I believe your warning is very important, and it should be added to our list of drug warnings--I expect John Cottingham will do that? Is it possible that the Hytrin interacted with the sinemet? You seem to suggest that possibility. I wish there were something helpful I could say--but please know that we are here to listen, and do keep us informed how things go. Perhaps others will have expertise about the meds/interactions, or ideas where to seek further information. Stay connected... Camilla Flintermann, CG for Peter, 78/7, Oxford,Ohio [log in to unmask] * * * * * * * * * * * * * * "Ask me about the CARE list for PD caregivers!" * * * * * * * * * * * * * *