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I am not a medical doctor but I have major skills in systematic thinking. In dealing with my own Parkinson's, I have generated some possible ways of thinking about Parkinson's and Candida that might help SOME people in this network. First a quick set of definitions. Candida, or Candidasis, is an overgrowth of a fungus that occurs normally in all people. Several types of stressors can cause the Candida overgrowth which often occurs in the bowels. The problem then can cause constipation and malabsorption of vitamins and other nutrients, as well as the absorption of toxins and undigested proteins into the blood. It struck me that if undigested proteins were getting into the blood, they could easily compete with the Sinimet at the blood-brain barrier causing a decrease flow of Sinimet into the brain and a resulting exacerbation of Parkinson's symptoms. The implication of this line of thinking being correct is that if a Parkinson's patient has serious problems with on-off cycles and especially neurological-cognitive-mood shifts, the problem might be indirectly linked or directly linked to Candidasis IN "S O M E" PARKINSON'S PATIENTS. Then if this is true, those patients should be treated for Candidasis. Tom Kohler, PhD