The following may apply here. This is a letter received from Univ. Of San Francisco Parkinsons Disease Clinic in Feb. of '95. Dr. Michael Aminoff (MD), Director, and Dr. Glenna Dowling (RN, PhD), Cooridinator both signed it. I have not heard anything further on this - has anyone else? Roberta - CG for Clyde 64/5+ ps - according to the Professionals Guide to Patient Drug Facts- Hytrin (Terazosin) is an "Alpha-1-Adrenergic Blocker, used to treat high blood pressure, which dilates both veins and arteries to reduce resistance against which the blood must flow. It also relaxes the muscles around the urethra and improves symptoms of benign prostatic hyperplasia (BPH), or swelling of the prostrate in males." As with most drugs, the 'possible' side effects listed are numerous. I urge all of you, if you haven't already done so, to invest in one or more PDR/Drug Interaction references, and keep them current - new drugs come along every month it seems. I am not exactly saying I don't trust the Doctors, just that it always pays to do your own checking. Letter from UCSF February 1, 1995 "To our patients: We have recently been informed by Somerset Pharmaceuticals that the drug Eldepryl (Selegiline) may rarely be associated with serious toxicity when used in combination with certain antidepressants (see examples below). If you are taking Eldepryl in combination with any of these drugs, please call the prescribing physician for advice as soon as possible." Tricyclic Antedepressants: Generic Name (examples) Trade Name (examples) Amitriptyline Elavil Endep Amitriptyline/perphenazine Entrafon Entrafon-Forte Triavil Amitriptyline/chlordiazepoxide Limbitrol Amoxapine Asendin Clomipramine Anafranil Desipramine Norpramin Petofrane Doxepin Adapin Sinequan Imipramine Tofranil Nortriptyline Aventyl Pamelor Protriptyline Vivactil Trimipramine Surmontil Trazadone Desyrel Seratonin Reuptake Inhibitors Generic Name Trade Name Fluoxetine Prozac Sertraline Zoloft Paroxetine Paxil Venlafaxin Effexor