Hello Brian, Brian Collins wrote: > 1/ I often experience back pain when trying to do things like yard > work, and it is much worse if I am in the 'Off' condition. I believe > that the cause is fairly straight forward; the typical Parkinson > posture - leaning forward from the waist. Try catching a glimpse of > yourself in a window or a mirror, and you will be surprised at how > far from upright you are. This lean puts heavy stress on the lower > back area, -the pain is your body's way of telling you to quit! ....... > For what it is worth, I think the reason that we tire so quickly is > that our muscles are already exerting effort, pulling against each > other, so that when we exert a force on say a shovel, we have to > produce the opposing forces, Plus the force to move the shovel. > > The amount of dopamine used by the brain has virtually no relationship > to the amount of effort being expended by the body. The dopamine is > actually used to condition the fluid in the synapses so that the > electrical signal from the brain is conducted correctly across the > synapse. Say Brian,how would you explain the drowsy effect many in the list do feel after taking sinemet and passed say about 20 to 120 minutes(it varies) ??. Regards, +----| Joao Paulo de Carvalho |------ + | [log in to unmask] | +--------| Salvador-Bahia-Brazil |------+