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The cause de PD is unknown, but: 1.- Although the term " Parkinson=B4s Disease" is commonly employed, the= re is no convincing evidence that the disorder is a single entity with one cause. 2.- Both basic and applied research point to an etiology in which multip= le risk factors may be necesary for the expression of disease. 3.- The MPTP story put the idea of a specific neurotoxin firmly on the ma= p. 4.- Support for an environmental cause also comes from studies that show = PD crossing racial but not geographic boundaries. 5.- Factors associated with PD occurrence in analytic epidemiology studie= s include rural residency, potable water source from a private well, participation in farming and exposure to pesticide products. 6.- The work " Environmental antecedents of young-onset Parkinson=B4s disease" P. G. Butterfield, Neurology 1993; 43: 1150-8 supp= ort the hypothesis.This study provides evidence on behalf of an association between pesticide exposure, most prominently to insecticide products, and PD. 7.- An alternative hypothesis is that exists one o more environmental toxins to which we are all exposed but that some of us cannot cope with. The inability to handle relevant toxins may be an inherited trait, raisin= g the role of genetics in PD. 8.- The findings of an inverse association between cigarette smoking and = PD risk are among the strongest found in the PD literature. First noted in 1966 by Kahn. At 01:07 PM 3/18/97 -0500, you wrote: >------------------------ > >I would appreciate anyone's comments regarding any correlation between >persons having PD and also having an extremely sensitive reaction of the= ir Santiago Mola=20 [log in to unmask]