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I've been taking baclofen for several years for foot cramps. I experienced the cramping in the early morning, and I found if I took it at bedtime the therapeutic effect didn't last that long. Now I take five 25 mg. pills between 12 and 1 a.m., along with one sinemet CR (25/100). I then take a nibble of a sinemet 10/100 at 4:30 a.m.and a CR at 5:00. It seems to be doing the trick so far. Good luck. Pat Schark P.S. An additional boost comes from two tablespoons of vinegar, also recommended for foot cramps, which I take with the bacolfen. pine`