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Scientific American article I finally saw the article on PD in Scientific American (Jan 1997). It's a pretty good summary, better than I expected. Quite a bit of space on the controversial oxidative stress hypothesis (you'll see why shortly). Proposed reason for failure of the antioxidant vitamin E to slow progression of PD is, it doesn't cross the blood- brain barrier; very plausible. And some authorship surprises: Up to now, I thought the main credit for introducing levodopa should go to G. Cotzias, but this article gives most of the credit to Swiss neurologist W. Birkmayer. And I thought Birkmayer, as chief promoter and marketer of selegiline (Eldepryl), was responsible for its introduction, but in fact the authors of this article, M. Youdim and P. Riederer, discovered the value of selegiline and were awarded a medal for it. Needless to add, they still feel that oxidative stress may be an important causative factor in PD. Cheers, Joe J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks CA 91403