Dear MRS and MR Ashley, I dont know about "research" on people with PD but I've been using it for the past 10 or so weeks. My original purpose for taking it was to try and combat the unrelenting fatigue I was experience. As you know Ritalin as used by most adults acts as a stimulant and I was hoping to keep my eyes open during the day. The Ritalin did even better for me......It reduced the Fatigue by about 70-80% and then continued to move on reducing other swmptoms. my Blepharospasm? diplopia avoidance? or as I prefer to call "DIRT IN THE EYE? [Haven't figured what that is all about ....yet.I mo longer experience any eye closings while the drug is still working [about 3 hours] unless I'm under stress. AND this has led to a chain-like effect. Fatigue---->eyes----->UNfroze my forehead[part of the mask?] ----->I stopped yawning---->stomach muscles Relax------>toes uncurland stop clenching------> MY WALKING/ WALKING BACKWARDS becomes easier ------> I'm a happy man. Of course this response is co-produced by daily exercise, good eating habits,other meds, a very positive attitude and a whole lot of support from family, friends and "my team" of health care providers. And yes, the chain ettect works in reverse. I shut down in stages. Actually a bit funny . My eyes close and within a matter of seconds I start to yawn and at the other end my toes curl!! BY THE BY I'm well in to my 50ies and have had 2 Pallidotomies. One other thing Ritalin is a controlled drug and can be tricky. On the other hand it has a half-life of 2-4 hours. Of course You should not take the above as an endorsement of Ritalin. As I'm sure you know each PDer reacts in their own sweet or not so sweet manner Hope the Above is useful to you all. george [log in to unmask] AMAZING GRACE Amazing grace, how sweet the sound That saved a wretch like me I once was lost, but now I'm found Was blind, but now I see