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Camilla Flintermann wrote: > > Friends--I'm posting this to the main list rather than CARE in the hope someone > can shed light from personal experiences. > Yesterday Peter had to have an energency extraction of a broken tooth. The > oral surgeon and staff were most accommodating, sensitive to his needs, etc. > and the procedure went well, at 8:00 AM. We were home by 10:00AM, and as > he was still dopey from the anesthetic he slept off and on all day and evening- > -he did take his Sinemet 10/100 every 2 hours as usual,but no extra doses. > He was also on a crash dose (7 AM and 1PM)of Amoxycillin antibio., as he has > mitral valve prolapse, and this is required before any oral surgery. > He was a bit spacey off and on yesterday, due to the anesthetic--and po > also the stress of the situation. This AM he woke feeling quite normal, took > 10/100at 6 AM,8AM, 9:45 (before I left for church) and seemed fine. When > I returned home about 11:30,in time for his next dose, he was in trouble, > said his legs weren't working, couldn't stand to get out of his chair in living > room.....I gave him the next 10/100 early, at 11:45, dealt with other > problems, and a half hour later he still was too wobbly to stand with my help. > I recalled that this was how he was the time he had to wait for the doc to > discharge him from a day of hospital observation, as the stress of waiting till > 9:30PM for the doc really got to him. On the theory that the stress level may > (like hard exercise has been said to do) cause the Sinemet to not work as well, > be used up faster, whatever, I persuaded him to take another 10/100 at 12:15, > then sat quietly, played soft music, talked reassuringly. Within a half > hour, he was able to get up and get from the living room to the bathroom with > my help,legs functioning OK! > Here's my question--could it be that stress levels affecthehe way t > Sinemet is used by the body---so that in a highly stressful situation one > might be *undermedicated* even with normal doses? I should add that Peter has > never had dyskinesia, nor does he have more than very minor resting tremor of > hand when eating. His main problems are bradykinesis,bradyphrenia,and > rigidity. (Plus others too numerous to mention!) > If it seems this is a reasonable deduction from our experience, I can be > prepared to ask neuro to increase his doses during the stressful time when I > will be having surgery in April, and he has chosen to spend three days time in > a local NH, rather than try to cover(for that short time)24 hrs. a day here at > home. Any light that anyone can shed on this subject will be very welcome! > > Camilla Flintermann, CG for Peter, 78/7, Oxford,Ohio > [log in to unmask] > * * * * * * * * * * * * * * > "Ask me about the CARE list for PD caregivers!" > * * * * * * * * * * * * * * HI Camilla, I've enjoyed reading your informative notes for a while. I am a young onset pd'r age 39 (yesterday) I seem to notice that when I am doing my landscaping work, my body doesnt react as well to the sinemet, Now let me explain when I an landscaping its in the 90 degree sun and i am hauling rocks around, digging and other types of physical labor. After about 3 hours I get clumsy, start tripping over things and generally on the road to an accident (a fall or whatever) I drink plenty of water and gaterade, but i do think that it does something to wear off the drugs quicker. I dont know if this relates to you at all ... lisa in paradise [log in to unmask]