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Hi Don, I read your post to Peter, who agrees that being "off" affects him mentally as well as physically. Responses, cognition, etc, are slower, memory is worse. Seems to be "part of the package" st least for some PWPs. Hang in there! Camilla Flintermann, CG for Peter, 78/7, Oxford,Ohio [log in to unmask] * * * * * * * * * * * * * * "Ask me about the CARE list for PD caregivers!" * * * * * * * * * * * * * *