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I was diagnosed as Parkinsonian at age 63 - some 3 years after my personal observation of tremor and "frozen shoulder syndrome". Combinations of bromocriptine(Parlodel), amantadine(Symmetrel) and selegiline(Eldepryl) worked for the better part of 4 years. I discontinued the Parlodel because of some evidence of retroperitoneal fibrosis and reduced the amantadine when my ankles began to discolor a bit. I discontinued the Eldepryl last year when my hypertension worsened. I will be 71 in June and am now at 1400 mg Ldopa/140mg carbidopa; 100mg amantadine; 50mg atenolol and 5mg Norvasc - the last two are for hypertension. I tried Permax but was not able to achieve a workable balance with the Ldopa. Amen Patrick J Martin<[log in to unmask]> 71,11,8