Dear Helen, I've read, in a prior posting to the list, that GPI-1046 is supposed to begin being tested on humans late this year. In other words, they've just completed the rats and mice trials. I've also heard that in will probably be 10 years before this possible "Cure" for P.D. is available to the public. ^%$#^*%$% FDA. I think we need to get our message across to them, that, as most of them sit around the table, thinking up ways it could be harmful (I am convinced that's what they do), we are suffering. Jacob