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IN MY CASE, YES, I TRIED SINEMET & IT DIDN'T DO ANYTHING FOR ME EXCEPT MAKE ME NAUSEAUS. OTHER NAME FOR SYMMETREL IS AMANTADINE. IT WORKS TO MAKE IT EASIER FOR DOPAMINE PRODUCING NERVE CELLS TO OPEN WINOW AND RELEASE STORED DOPAMINE (OR SO THE SHEET SAYS) I'M NEW TO THIS DRUG REGIME. ALWAYS DID HATE TO TAKE MEDICINE & WHEN I WAS DIAG IN 1994 STARTED ON ELDEPRYL 5MG X 2 PER DAY AND FOR ME IT WORKED W/ NO SIDE EFFECTS. THE SYMMETREL (SO FAR) HAS GIVEN ME BACK A LOT OF THE DEXTERITY LOST IN LEFT HAND & NOW LEFT ARM SWINGS WHEN I WALK WHICH IS GREAT!!1 I'M UNDER A LOT OF STRESS NOW & IT SURE AFFECTS ME!! I CONTINUE TAKING ELDEPRYL ALSO. MARY E SANFORD [log in to unmask]