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Jacob, Thank-you for the info. on Mirapex. My neurologist said the name made it sound like a miracle. We can only hope and hope it's available soon. I'm just taking Sinemet CR now as the Amantidine (sp) was making my skin splotchy and the toe cramps didn't feel too good either. I guess is depends what side effects you can put up with. Thanks again for the information. Patricia 60-three years