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HI RALPH I TOO WAS NAUSEAUS ON SINEMET 25/L00 SO I QUIT TAKING IT. DIDN'T SEE WHERE IT HELPED EITHER SO WASN'T WORTH IT. HAVE NOW ADDED AMANTADINE/SYMMETREL TO THE ELDEPRYL THAT HAVE BEEN TAKING SINCE DIAGNOSED DEC 1994. IT DOES WHAT I HOPED. MORE FLEXIBILITY IN LEFT HAND AND MY LEFT ARM SWINGS WHEN I WALK NOW. GOOD LUCK MARY E SANFORD [log in to unmask]