M E SANFORD wrote: > > JERRY I TAKE ELDEPRYL SINCE DIAG DEC 1994 AND I DID NOT RESPOND TO > SINEMET IT ONLY CAUSED NAUSEA AND A "WEIRD" FEELING. DIDN'T SEE ANY > DIFF IN PD WITH OR WITHOUT IT. I HAVE NOW ADDED SYMMETREL AND LIKE IT > WHAT HAPPENS DOWN THE ROAD TO PWP THAT DON'T RESPOND TO THE SINEMET???? > > MARY E SANFORD > [log in to unmask] Mary: You don't say what your symptoms were when diagnosed, but there is the possibility that you don't have PD. Other conditions resemble PD and it is very difficult to diagnose. You might want to get another opinion on the Dx. There is also the possibility that there are different forms of PD, and you have one that doesn't respond to Sinamet. The new dopamine agonists (Pramipexole & Ropinerol) show promise in working by themselves (or at least without Sinamet)..... Jerry Starr