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Brian you wrote Lyn with a list of the "mild" drugs that you have taken and said that taking these withthe belief that you get more out of the levedopa in later years is a waste. I was diagonosed 3 years ago and my doctor had put me on SInemet from the beginning and this fall I was taking 150/600 reg. Sinemet and 150/600 CR during the day. That has been cut back to 100/400 reg and 100/400 CR. I will be switching to a new Neuro and would appreciate a copy of the charts A and B that you suggested to Lynn. What you wrote about the meds you tried was helpful. I am doing my best to educate myself about the P medications before I go. With the reduction of my med I am having more problems with stiffness, tremor etc. From what you know is that usually the case. Is that drug PRANIPEXOLE really as good as some say? Thanks for you helpful words on the List. Brenda Otte [log in to unmask]