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To: J Bruman I am not aware of any evidence that vitamin supplements do any good, either for PWP or for people in general. In the January Scientific American article about Parkinson's, the author mentioned he was puzzled by this and suggested that maybe higher doses were needed. Another theory is that vitamins are less effective when they are taken separately to the substances with which they occur in natural foods. There is plenty of evidence that foods containing antioxidants such as green veg, fruit and oily fish are beneficial to people in general. I had not previously seen any study of their effect on PWP. In your most excellent review of scientific papers, you refer to a paper in Movement Disorder which found that dietary antioxidants were not protective. Please would you clarify whether the dietary antioxidants were in the form of vitamin supplements or in the form of natural foods high in antioxidants. Does anyone know any good evidence for the benefit of antioxidants in the form of vitamin supplements? Jamie Carnwath 46/9 [log in to unmask] Cambridge, England