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Richard: I have experienced the tightness around my neck and also the squeezing around my head. Don't think I've felt it much in the ribs, nor the thumping heart. I really can't account for WHY I have this tightness. As I have at various times reported previously on this list, I have been troubled by neck and throat pain for years. Let us know if you find a solution. Barbara Blake-Krebs [log in to unmask] On Wed, 23 Apr 1997 Richard Doyle <[log in to unmask]> wrote: I take Sinemet 25/100 4x daily, sometimes I use the CR. I stopped Permax 1 1/2 months ago because it seemed to make worse the symptoms I'll describe. Additionally, I had quadruple bypass surgury, with a valve replaced. I have tightness around my neck like a band being pulled tight -- then this feeling moves up to my head, squeezing my head tight. This makes my vision blurry. My lower ribs also feel like there's a band tightening. My heart valve then thumps so loudly that it scares the heck out of me. When I was taking the Permax, all of this was painful. Then I stopped the Permax, and the symptoms went away. Now, much to my dismay, they're back, but they're not painful yet.