I have been taking Pramipexole for nearly three years, beginning with a double blind trial for three months, then a three year open-label trial. I had difficulty in writing, reduced arm swing and mild tremor, but only after diagnosis recognized my leg cramps and overwhelming fatigue were due to PD. I have responded to pramipexole very well: much more energy and sense of well being, no more cramping, and control of the tremor. I require 1.5 hour less sleep than before. It has not helped the handwiting. During the past winter I have had some difficulty with drowsiness when driving toward the sun when it is low in the sky, even when the sky is cloudy but bright. It hits me after about 20 minutes, and is worst on divided highways where the flow of traffic is smooth than on roads where stoplights and cars changing lanes seem to help keep me alert. The recent comments on who to tell have been very interesting. I am quite open about having PD with family and close friends but have not told my employer or work colleagues (except my assistant whom I felt must know). My symptoms are not yet evident to those who do not know, and to this point having PD has not impaired doing my job (I use a laptop for meeting notes). I haven't told my manager or fellow workers yet because I am concerned about the reaction -- will I be taken less seriously or not given opportunities because people will assume I can't handle the load? I know at some point I will have to -- but am inclined to wait until there is a reason to explain. This list has been really helpful to me because even though my family and friends are very supportive they do not really know what it is like to have PD and I have got so much useful information and insight from you all. Margaret Caughey (60/3 Pramipexole 1.5mg x3)