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Hi, Mary (et al). You asked, in your post to the PD Digest, about colloidal NADH. I've had my mom using colloidal NADH for more than a month now, and it really seems to be having a good effect: It cut down on, and often entirely eliminates, tremors at night, and it seems also to be cutting down on daytime tremors too. I still am gradually adjusting the dosages to try to fit her needs, but generally I give 4 droplets (under the tongue) every 3 hours (except in the wee hours). This is in addition to her every-3-hour doses( except in the wee hours) of Sinemet-regular. I've read that Dr. Earl Mindell recommends that for NADH in general, one should gradually increase the dose (within limits) up to the point at which dyskinesia appears, and then gradually reduce to a non-dyskinesia level. Others suggest gradually increasing (within limits) up to a level that seems good and keep it there. The brand of colloidal NADH that we use is Liquid Lightning Colloidal NADH, produced by Inner Light International of Alpine, Utah. They can be reached via 1-800-677-0997. I also have located, on the web, the site of another firm that markets colloidal NADH (which may also be the same Inner Light Int'l product),"Chronic Wellness International"; I found them (via a search-engine) at this webaddress: <http://www.ourworld-compuserve.com/homepages/chronicwellness/nadh.htm> I've been trying to keep up with the NADH research, and generally it seems to me that NADH can indeed have positive results, and I've seen it with my mother (who has PD). But I think you'll do well to research it to your own satisfaction. Good luck. -- SJS 5/1/97