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Dear Ray, I know what it is like to have an excess of dopamine. After the poisoning and subsequent damage to my globus pallidus, I was given sinemet by a well meaning but ignorant physiatrist. Well, it was not enough to give me Tourett's per se, but a constant stream of obscenities came out of my mouth. It was all I could do to keep from saying them outloud. Most often they came out in a whisper. Thank you for the information on the PBS special. Jacob