Thanks for your reply. I have done a great deal of reading on antioxidants, for quite a few years, now. My husband is a biochemist and biomedical researcher and a lot of what he finds out makes its way into my brain after awhile (and after many repetitions!). We find that the Coenzymated B-3 by Source Naturals, a sublingual form of NAD (nicotinamide adenine dinucleotide) with inositol hexonicotinate does a good job for my dad's restless sleep. He can dissolve one under his tongue when he wakes during the night ("and it's oh, so minty!"). It runs just under $12 for 30 and is available in many health food stores. I would like more information on the negative tryptophan/l-dopa connection. There is a popular notion is that tryptophan is no longer available since the FDA removed it from shelves after the eosinophil syndrome episodes several years ago. It is true that even though the problem was traced to a faulty filtration system in the Japanese manufacturing plant, the FDA never released it again for over-the-counter purchase. But it is available by prescription. I fully agree that the digestive system is the place to look, not necessarily for the ultimate answer (we don't know what that is, or we wouldn't be where we are!), but for the role it plays in healthy and ill states (PD or not). Disgestive enzymes are often produced less as we age, so breakdown prior to absorption is negatively affected. That means that important nutrients -- and pharmaceuticals -- are less likely to be absorbed so they can do the good for which they are ingested. I have had a copy of Prescription for Nutritional Healing for several years and agree with a substantial portion of it. I disagree with some parts, but that would be predictable. I have used Life Extension by Pearson and Shaw fairly extensively, and currently recommend The Zone, a best seller by Barry Sears. As to the amino acid drink, that is a liquid form of protein. I have noticed for two decades that the people who are most depleted nutritionally are the ones that tend to have the most dramatic response to introducing denser nutrients into themselves. That leads to all sorts of "miracle" claims that make me uneasy. Dixie Lawrence (who has now married and I cannot recall her new last name) has been profiled on television news magazines for the nutrient combination she devised for her adopted daughter with Down's Syndrome. Other parents tried it. Their children tend to thrive (unlike typical Down's kids), have more subtle physical signs of the anomaly, and make the honor roll. At first the official Down's Syndrome organization rejected her work because it had not gone through large clinical controlled trials. Because so many lay people could replicate her results (which cannot be faked), the official group "broke down" and had Dixie provide the keynote address for its last conference. Her story can be found at www.ceri.com (ther is also information there that directly relates to Parkinson's). The above is an example both of what a profound role nutrients play in our states of being, and of what one person with determination can accomplish. You remind me very much of Dixie. I believe some of my confusion about your previous post was because I am a hopeless reader when punctuation is scanty. It is not you who needs to change, here, it is that I need to suspend my very literal mind when I read posts from you (or Bob--hi, Bob, I love how you spell!) -- and I need to ask questions whenever I am confused. So, rewind, if you are so kind, and change my "irresponsible" charge to "confusing". I appreciate two things: 1) you didn't flame me and 2) you cleared up some of my questions. Wanna talk about the male/female benefits of DHEA/pregnenolone? Deanne Charlton [log in to unmask] ps. Do I take it that your name is Linda and you have a child named Forrest? Not that you have a child named Linda Forrest?