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In a message dated 97-05-20 07:56:58 EDT, Jim wrote to David: << Selegeline Hydrochloride (Eldepryl, et al) can delay Parkinsonian disability and the need for levodopa therapy by 9-12 months if given in the early stages. Later, in combination with levodopa, it can reduce levodopa requirements by 20-50%, and reduce levodopa's side effects. It may have a neuro-protective effect. One of the side-effects can be insomnia. >> For more on eldepryl, its side effects and a different form of it that seems to have greater positive effects w/ fewer side effects, try www.ceri.com for their information on PD. Deanne Charlton [log in to unmask]