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Stephen-- as CG, my cramps in calves have nothing to do with PD, but I think they are fairly common...a couple of things in case you haven't tried them---putting weight on the leg relieves the cramping, and it can even help to flex the ankle forward while lying down. Sometimes doing some calf- stretches against a wall before retiring will help. But what a PAIN! it is MISERABLE! Hope this may help--- Camilla Flintermann, CG for Peter, 78/7, Oxford,Ohio [log in to unmask] * * * * * * * * * * * * * * "Ask me about the CARE list for PD caregivers!" * * * * * * * * * * * * * *