I'm new here and so glad to have found this list. I live with Virginia 78/8, my mother. I would appreciate hearing anyone's experiences/knowlege about the drug oxybutynin (Ditropan) or with the drug propantheline (Pro-Banthine) in conjunction with Sinemet and Parkinsons. If it's of interest: My mother's drug regimen is Sinemet CR, Naproxen, a calcium supplement tablet, Premarin, plus very occasionally a muscle relaxer tablet at bedtime (the word Flexiril comes to mind, but that may not be it), and rarely one Trazadone. Ditropan and Pro-Banthine are two types of bladder muscle relaxers, prescribed for people with detrusor hyperreflexia. My layperson's interpretation of detrusor hyperreflexia is: involuntary contractions of the bladder detrusor muscle, which are one cause of urinary frequency and urges. Best, Lynne Motley [log in to unmask]