I would like to intoduce myself to the list and ask if anyone would care to comment on my case history. About two years ago, I went to a neurologist because I was experiencing rigidity in my right arm. The doctor did not feel I had PD for various reasons including the unilaterality (right side) of my disability, but he prescribed sinemet as a means of eliminating the possibility of PD. I took substantial doses of sinemet for about five weeks but did not notice any improvement and quit. My neurologist indicated that my condition might be cortical basal ganglionic degeneration. Last year with increased disability, I went to another neurologist who felt I had PD and again prescribed sinemet. Again I took sinemet faithfully for over a month, but again stopped when all I experienced was nausea. A few months ago, having lost nearly all ability to write, I started taking Parlodel (bromocryptine) for the tremor I was experiencing. The Parlodel seemed to help as my tremor lessened. About a month ago, I went to another neurologist who felt I had PD and again prescribed sinemet. My reaction was dramatic. Within ten days, my medication was eliminating at least ninety percent of the symptoms that I had been experiencing. I am still a little dazed with thankfulness for a substantial part of my life being restored. I am also wondering why sinemet had no effect on me earlier and how much to attribute its present effectiveness to parlodel working as an agonist. I've only been reading this list for about ten days, but during that time, there has been little mention of parlodel. Do many PWP take parlodel, and what are their feelings about it? I am grateful that this list exists, and now that I am a pill carrying member of PWP, I hope that I can contibute to it. Jim Traweek, 52 Seattle, WA