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Hi Jim: I find your experience really puzzling because the order in which you started your medications is the reverse of what is usual. Being a non-medical person myself, I can only tell you that as a lay person with PD it suggests to me that you had too much dopamine evidentally naturally occurring in your system! Otherwise, I can't phathom why the Parlodel alleviated symptoms when you were NOT taking sinemet. Because I take Parlodel too, I once asked my PD specialist whether Parlodel could ever be taken alone for PD and as I recall he said "no." You mention that you have seen some neuros. Have any of these been Movement Disorder Specialists or PD Specialists? I would urge you to consult with one. I imagine that people from the Seattle area on this list can give you some recommendations. Good luck! Barbara Blake-Krebs (56, 13) [log in to unmask] on Sat,31 May 1997 15:19:53 -0400 Jim Traweek <[log in to unmask]> wrote in part: <<A few months ago, having lost nearly all ability to write, I started taking Parlodel (bromocryptine) for the tremor I was experiencing. The Parlodel seemed to help as my tremor lessened. About a month ago, I went to another neurologist who felt I had PD and again prescribed sinemet. My reaction was dramatic. Within ten days, my medication was eliminating at least ninety percent of the symptoms that I had been experiencing. I am still a little dazed with thankfulness for a substantial part of my life being restored. I am also wondering why sinemet had no effect on me earlier and how much to attribute its present effectiveness to parlodel working as an agonist. I've only been reading this list for about ten days, but during that time, there has been little mention of parlodel. Do many PWP take parlodel, and what are their feelings about it? Jim Traweek, 52 Seattle, W>>