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Stephan Schwartz wrote: > > >>Cathy Bradley/Mary G. wrote: > >>Please explain the difference between Sinemet and > >>Sinemet CR<< > > Hi CB/MG: > > Levodopa is universally recognized by researchers as the > most effective treatment for PD. In order to inhibit the > metabolism of the levodopa outside of the brain, carbidopa is > added. This medication is available as Sinemet in three > ratios: 25/100 (carbidopa/levodopa), 25/250 & 10/100. At > least 75 mg of carbidopa per day is necessary to prevent > metabolism of levodopa outside the brain. > Good luck. Stephan 52/6 Hi Stephan, I have a question about the assertive that at least 75 mg of carbidopa is really necessary in the case of a PDer with mild or light PD and taking a lower amount of levodopa,say less than 200 mg of levodopa/day.Are these figures accurate ? How about Madopar that uses chloridatre of benserazine instead of carbidopa ? Warn regards, +----| Joao Paulo de Carvalho |------ + | [log in to unmask] | +--------| Salvador-Bahia-Brazil |------+