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> I saved your letter until I could get back to it. I had smell troubles > after I began taking the Eldepryl. I recall how exrtreme it was. > Mettalic and sometimes chemichal..like nichotine. I also could taste > chemicals. Even today..in the center of my tongue is a slight burning Hi Carol, I am unwilling to discuss particular problems associated with pharmaceuticals. I don't have enough money to risk being sued. The smells to which I and others referred are just false messages to the olfactory system. Your problem seems much more serious. There is a general warning for interaction between TCA's (tricyclic anti-depressant) such acs imipramine, and MOA's (monoamine oxidase inhibitor) such as selegiline hydrochloride (eldepryl) . The effects are much as you describe. However, they don't affect everyone equally or at all. For example, I take Sinequan, a TCA, and Eldepryl, a MOA, and don't have any adverse reaction that I am aware of. I am not aware of any particular side-effects of Eldepryl taken alone, but when we consider any medication that affects the brain, I suppose anything is possible. I know what you mean about not being taken seriously by doctors. What one does in a town where one's choices are limited, I don't know.