Just visited my doctor today. Dr. O'Brien, Movement Disorders Section, Colorad Neurological Institute, Swedish Memorial Hospital, Denver Finally felt I needed an anti depressant. Went on Zolofft 17 days ago and my tremor (left hand) went out of sight. lip tremor returned. peculiar feeling when walking returned. 50mg Bad. 25 mg pretty bad -- ok for depression. Today, Dr. O'Brien put me on Welbruton and said it should improve the original state of my tremor (Before Zolloft -- BZ). Told me that no indication Ropinerol will stop progression and at some point I will probably need to add another drug. Disregarding my current reaction to Z, my last exam still resulted in "mild" after 5? years {have to sit down and figure it out}. Before I went on Ropinerole -- 30 days after diagnosis at Mayos and Sinemet -- I qualified as an experimental patient since I had not been on Sinemet more than 30 days. Before diagnosis and Sinemet: Loss of sense of smell, My voice was becoming very low or soft. worse tremor in left hand than BZ and peculiar feeling when walking lip quivering. Today, I felt pretty much as I did before my diagnosis -- except the tremor was worse. During the interim, I had none of these symptoms except left hand -- much less than today. One other point, I am a recovering alcoholic of some 18 years. I have been on Eldepryl 5mg times 2. plus final dosage of Ropinerole of 8mg AM, 7mg at noon, 7mg at supper. My blood suggar has been going up, but I have had problems for years and don't blame Ropinerole.. Now I have to deal with it as it is worse. Blood pressure today was -- cant keep them straight 61/141 or 141/61? I have never had any of the on/off problems with Ropinerole (knocking on wood). Sleepiness yes. Some insomnia at night. voice has been good (exercise by singing in car when alone)--except for the past week when it has been weak again. do have many of the other litle things, drooling, problems tying tie. But I have done very well (slight left hand tremor). Hard to get out of bed or a car. Sore muscles. Have massage l time per week and try to work out (moderately 2 or 3 times per week. As to your last question, Ropinerole is made by SmithKline of King of Prussia, Pa. It is my understanding that it is supposed to be released this summer. Keep your fingers crossed. It is a great medicine -- that is my conclusion. Jack Stanfield ([log in to unmask]) Laramie, Wyo. age 62