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It's all great and I'll bet if he stopped taking them he would not feel as good. My husband takes those as well as nadh, sun chlorella a, pycnogenol, l-carnitine, liquid deprenyl, a multi-mineral and actually a few others I can't remember. Yes, lots of pills and expensive. He has been able to take less sinemet though and his energy is great. We keep searching and even experimenting and reading and waiting for something definitively new and effective to emerge. I love the list and all the opinions and information. As always, we must do what feels right for us and just pass on what occurs if it's positive. I love hearing about the more natural methods people use to control symptoms etc. as well as the more conventional drug therapies. Den