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Recent postings about generic Sinemet have made me wonder about its effectiveness. I recall a private conversation with someone on this list who detailed the ill effects of generic Sinemet. My mother Joyce, 67/around 4 months, takes the generic version — she has never tried anything else. What I'm wondering is, is it worth trying regular Sinemet to see whether the PD symptoms that remain with generic Sinemet can be eradicated with the other version? And how does one go about doing this? Simply replace one for the other for a certain period of time? Has anyone tried this? Or is it the case that the regular Sinemet probably wouldn't address the PD symptoms better than the generic version, but rather that the generic version can sometimes produce undesirable consequences? Debbie White [log in to unmask]