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>A bit technical, but the words I understood sent a clear message: dietary
>Vit. E intake
>is important & beneficial.
>
>Abstracts - June 1997
>Dietary Antioxidants and Parkinson Disease
>
>The Rotterdam Study
>
>Maarten C. de Rijk, MD; Monique M. B. Breteler, MD, PhD; Johanna H. den
>Breeijen, MSc; Lenore J. Launer, PhD; Diederick E.Grobbee, MD, PhD; Frans G.
>A. van der Meche, MD, PhD; Albert Hofman, MD, PhD
>
>Objective: To investigate whether high dietary intake of antioxidants
>decreases the risk of Parkinson disease (PD).
>
>Setting: The community-based Rotterdam Study, the Netherlands.
>
>Design: The cross-sectional study formed part of a large community-based
>study in which all participants were individually screened for parkinsonism
>and were administered a semiquantitative food frequency questionnaire. The
>study population consisted of 5342 independently living individuals without
>dementia between 55 and 95 years of age, including 31 participants with PD
>(Hoehn-Yahr stages 1-3).
>
>Results: The odds ratio for PD was 0.5 (95% confidence interval [CI],
>0.2-0.9) per 10-mg daily dietary vitamin E intake, 0.6 (95% CI,0.3-1.3) per
>1-mg beta carotene intake, 0.9 (95% CI, 0.4-1.9) per 100-mg vitamin C
>intake, and 0.9 (95% CI, 0.7-1.2) per 10-mg flavonoids intake, all adjusted
>for age, sex, smoking habits, and energy intake. The association with
>vitamin E intake was dose
>dependent (P for trend=.03). To assess whether the association was different
>in participants with more advanced disease, we excluded those with PD who
>had a Hoehn-Yahr stage of 2.5 or 3. This did not fundamentally alter the
>results.
>
>Conclusion: Our data suggest that a high intake of dietary vitamin E may
>protect against the occurrence of PD.
>
>Arch Neurol. 1997;54:762-765
>
>
>
>
>Margaret Tuchman (55yrs, Dx 1980)- NJ-08540
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>