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> Actually, it is quite similar to an MRI.  BUT, I had to be motionless for
2.5
> HOURS, my head was TIED down, and they inject a chemical into a vein in
one
> arm while taking blood out of an artery on the other.  This is also a
> continuous process.
>
> And all of this happens AFTER you've been without food or medication for
over
> 12 hours.
>
> I had severe diarrhea and dizziness after it was over.  NOT a fun-filled
day.
>Jim Finn

REPLY

I have had 2 PET scans at Johns Hopkins in Baltimore. The PET scan is a bit
slow compared to a high power MRI  machine. The 'chemical" they inject can
be flourodopa or any one of several others or combinations. The "chemical"
has many of its atoms treated with a cyclotron [atom smasher] to change the
isotope of some element to a highly unstable one which will emit gamma rays
detectable by the PET scan detectors.  The studies I participated in used
the carbon atom [normally carbon 12] changed to carbon 11...This is usually
written with the "11" as a superscript IN FRONT of the C for carbon.  The
carbon 11 used in my study had a half life of about 22 minutes. This means
that one-half of the "chemical" has been used up in producing gamma rays in
22 minutes. In 44 minutes 75% is used up, in 66 minutes  87.5% has been
used up, etc. The amount of gamma rays sent out per time period is
falling... The initial gamma ray count per second drops 50% in the 1st 22
minutes, drops to 50% of the 22 minute rate at the end of 44 minutes, etc.
In theory I am still giving off gama rays fom my first PET scan which was
over three years ago. [like to story of walking 1/2 of the distance to an
object every minute.. you never get all the way there but you get very very
close].

There is a big problem with the detectors. There are lots of gamma rays
around us all the time,but the detectors want to count only the ones from
the "chemical." THe gamma rays they want to count come from very tiny
explosions when the atoms are reverting from one stage to another. The
explosions are in some ways like a shot gun. [With a shot gun, the
explosion inside the shotgun shell sends projectiles out one end of the
barrel. There is a "kick" from the gun in the opposite direction.]  The
tiny explosions in the "chemical" send out two gamma rays with each
explosion. The gamma rays are going in opposite directions [remember the
equal and opposite direction we learned in science so many years ago?] The
PET detectors are set up in pairs, one on either side of the location to be
studdied. The PET computer does not count a gamma ray particle unless there
are two at exactly the same time moving in opposite directions, thus
leaving out random ambient radiation.

Knowing something about what is going on makes the experience more
interesting. Knowing why makes it more of an adventure. The "taking out of
the other arm" part is to measure general concentration in the body as
opposed to the particular part being studied. The operators at Johns
Hopkins gave me a choice classical, soft rock, or elevator music. I chose
the classical.

Will Johnston



 Jim Finn