Regarding Ida Kamphuis' "Re: Diphasic Dyskinesia"... I couldn't agree more
with you, Ida. I've always been in a quandary with regard to the 'overdosed
dyskinesia' [tardive dyskinesia] relationship. I experience far worse
periods of dyskinesia during my "wear-off" time in the evening: typically
3-5 hours after my last dose [5-6 PM] of levodopa. It used to last at least
one half hour but never more than one hour. However, this May something
happened... the dyskinesia sets in about 3 hours after last dose, is a
terribly exaggerated version of the old dyskinesia, i.e., my limbs thrash
around quite violently, my torso writhes and my head bobs uncontrollably
[gives rise to very sore neck]. When I [try] to walk in this state, I
violently goose step, threatening the poor floor. BUT... the real kicker
with regard to this new symptom is... it can last nearly all night and
prevents sleep. If it doesn't stop after several hours in bed, I can usually
quell it by taking a 25/100 Sinemet... within 30-45 minutes it usually
begins to diminish thereby allowing me to fall asleep, but frequently
returns in several hours.
By-the-way, Ida... what is your new med scheme??? I also experience
debilating cramps in my right foot in the morning. It is really strange, in
that for the first 15-30 minutes of the day, I'm able to ambulate without
impediment [you couldn't tell from my gait that I was a PWP] but inexorably
my feet/legs poop out and I'm rendered virtually immobile. I'm able to
counter the immobility with several tactics:
a) walk backward
b) Take a few moments to "psyche" myself up, i.e., stand up very straight,
place my seemingly palsied right foot next to my "more
normal" left foot
and tell myself that I'm going to walk normally... this
usually results in 5-10
"normal" steps before my right foot cramps return and it falls into its
normal
trailing attitude behind the left foot.
c) start my drug regime for the day:
-- one 25/100 mg Sinemet turbo charger, one 2.5 mg Parlodel, one 5 mg
Deprenyl
-- one 50/200 mg and one 2.5 mg Parlodel one half to one hour later
and roughly every two hours
thereafter until 5 or 6 PM when I terminate all
drugs.
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David Barthuli
23 River Road
Merrimac, MA 01860-2229 US
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(508) 346-8209
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