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Sonia Nielsen wrote: > > ---------- > > Fra: Charles T. Meyer <[log in to unmask]> > > Til: Multiple recipients of list PARKINSN > <[log in to unmask]> > > Emne: Re: Paxil > > Dato: 5. juli 1997 12:51 > > > > Marling McReynolds wrote: > > > > > > Why did you stop the Eldepryl? > > Marling and others, > > > > There is a theoretical risk of taking a SSRI antidepressants such as > > Paxil, Prozac or Zoloft (as well as the older tricyclics) with > Eldepryl > > which is a selective monoamine oxidase inhibitor. However since it > > inhibits at low doses only one type of MAO it rarely causes > problems. > > Be careful to avoid doses (per day) of greater than 10 mg of > > eldepryl. > > Also Marling given the problem you have had with depression I would > be > > very cautious about giving up the Paxil for a trial of ST. John's > Wort. > > I also would be concerned about possible interactions between the > SJW > > the Paxil and the Eldepryl and possibly other meds you are taking. > > Since the mechanism of action of the SJW is not known you are > sailing in > > uncharted waters. My advise would be to let well enough alone. > > > > Charlie > > -- > > ********************************************************** > > CHARLES T. MEYER, M.D. > > MADISON, WISCONSIN > > ********************************* > > Hello Charlie, > sorry I have not been reading the first e-mails about Eldepryl. I hope > it``s OK to ask you if it`s normal that some people are going to be > depressed when they take Eldepryl. > I was diagnosed 3 1/2 years ago, and one year after my neurologist > told me > to start > Eldepryl. One week later I was depressed and refused to take the tabl. > He > told me it`s wasn`t "normal" that people became depressed. > I stopped, and after one week I was OK. > Now I have another neurologist and he has tried too to convince me > that > I`ll NOT be depressed, but still I say NO-thank you, and off course he > will > not force me because he knows me very well and we are real good > friends. > I`m looking forward hearing what you mean. > > Sonia Nielsen > Denmark > > NEVER GIVE UP HI Sonia, It is certainly not usual for someone to get depressed on Eldepryl. In high doses Eldepryl acts as an antidepressant. Having said that I firmly believe that because it theoretically shouldn't happen does not mean that the Eldepryl did not cause or increase your depression. Everyone reacts individually to a particular drug. It may have been a psychological reaction rather than a pharmacological one and if your neurologist feels strongly that you should take the drug you might consider it - but carefully starting with low dose and then gradually increasing. Charlie -- ********************************************************** CHARLES T. MEYER, M.D. MADISON, WISCONSIN **********************************************************