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Flo, Effexor is a different type of anti-depressant, not tricyclic as Paxil and Prozac. I am not sure what the differences mean, however there seem to be no contraindications for mixing Eldepryl and Effexor. Talk with your doctors and pharmacist, after all I am only a victim of this condition not a medical expert. don't forget how to laugh Marling [log in to unmask] (work) or [log in to unmask]